Commentary---anaphylactic reactions to paracetamol
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چکیده
منابع مشابه
Commentary-anaphylactic reactions to paracetamol.
Paracetamol is a widely consumed antipyretic and analgesic agent used either in combination or as a single agent. The general safety of paracetamol in therapeutic dosage has allowed it to become a freely available over-the-counter preparation. A safety evaluation of nonnarcotic analgesics in therapeutic doses ranked paracetamol as among the safest in their study. Most patients are not asked or ...
متن کاملAnaphylactoid reactions to paracetamol.
The toxic effects of paracetamol in overdose quantities are well recognised but the occurrence of anaphylactoid reactions to paracetamol is infrequently identified by consumers and health care professionals. Nevertheless adverse reactions to this drug, even in therapeutic doses, can have fatal or near fatal consequences. A case of an anaphylactoid reaction to paracetamol is described.
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The concept of elicitation of reactions of anaphylactic type by non-tissue-fixing antibody, through activation of complement and release of anaphylatoxins by antigen-antibody complexes in vivo, is not clearly defined by published evidence. Experimental data are presented to demonstrate that guinea pig immunoglobulin G2 (noncytotropic) complexed with antigen in vitro elicits dermal reactions in ...
متن کاملAnaphylactic reactions to proton-pump inhibitors.
OBJECTIVE To report two cases of anaphylactic reactions to proton-pump inhibitors (PPIs). CASE SUMMARIES A 54-year-old woman who had taken omeprazole in the past was treated with omeprazole 40 mg and developed periorbital edema, edema of the skin, pruritus, nausea, and vomiting about 45 minutes after taking one capsule. Five months later, she was treated with lansoprazole 30-mg capsules. Agai...
متن کاملAnaphylactic reactions to topical antibiotic combinations.
We describe two patients who developed anaphylaxis type reactions following the application of the topical antibiotic Polyfax (polymixin B and bacitracin). We draw attention to this potentially serious complication of topical antibiotic preparations and emphasize the need for careful history taking before prescribing such preparations.
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 2000
ISSN: 0032-5473
DOI: 10.1136/pmj.76.898.503